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DGAT2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DGAT2 Antibody (N-term) AP9686a
    Western blot analysis of DGAT2 Antibody (N-term) (Cat. #AP9686a) in NCI-H460 cell line lysates (35ug/lane). DGAT2 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96PD7
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 43831 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 84649
Other Names Diacylglycerol O-acyltransferase 2, Acyl-CoA retinol O-fatty-acyltransferase, ARAT, Retinol O-fatty-acyltransferase, Diglyceride acyltransferase 2, DGAT2
Target/Specificity This DGAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DGAT2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDGAT2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DGAT2
Function Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet
Tissue Location Predominantly expressed in liver and white adipose tissue. Expressed at lower level in mammary gland, testis and peripheral blood leukocytes. Expressed in sebaceous glands of normal skin but decreased psoriatic skin
Research Areas
Citations (0)

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Acyl-CoA:diacylglycerol acyltransferase, or DGAT (EC, is responsible for the synthesis of triglycerides. It catalyzes a reaction in which diacylglycerol is covalently joined to long chain fatty acyl-CoAs.


# Kantartzis, K., et al. Clin. Sci. 116(6):531-537(2009)
# Stone, S.J., et al. J. Biol. Chem. 284(8):5352-5361(2009)
# Yen, C.L., et al. J. Lipid Res. 49(11):2283-2301(2008)
# Levin, M.C., et al. Am. J. Physiol. Endocrinol. Metab. 293 (6), E1772-E1781 (2007)
# Payne, V.A., et al. J. Biol. Chem. 282(29):21005-21014(2007)
# Yamada, S., et al. Oncogene 23(35):5901-5911(2004)
# Wakimoto, K., et al. Biochem. Biophys. Res. Commun. 310(2):296-302(2003)

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Cat# AP9686a
(40 western blots)
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