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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   STX1A Antibody (N-term)   

STX1A Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - STX1A Antibody (N-term) AP9813a
    Western blot analysis of STX1A Antibody (N-term) (Cat. #AP9813a) in 293 cell line lysates (35ug/lane). STX1A (arrow) was detected using the purified Pab.
  • IHC-P - STX1A Antibody (N-term) AP9813a
    STX1A Antibody (N-term) (Cat. #AP9813a) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STX1A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - STX1A Antibody (N-term) AP9813a
    STX1A Antibody (N-term) (Cat. #AP9813a) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16623
Other Accession P32851, O35526
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 33023 Da
Antigen Region 29-57 aa
Additional Information
Gene ID 6804
Other Names Syntaxin-1A, Neuron-specific antigen HPC-1, STX1A, STX1
Target/Specificity This STX1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human STX1A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSTX1A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STX1A
Synonyms STX1
Function Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
Cellular Location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome
Tissue Location Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain.
Research Areas
Citations (0)

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This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis.


Yoshida, T., et al. Int. J. Mol. Med. 24(2):233-246(2009)
Hamdan, F.F., et al. Ann. Neurol. 65(6):748-753(2009)
Corominas, R., et al. Neurosci. Lett. 455(2):105-109(2009)
Chen, C.S., et al. J. Biol. Chem. 284(11):6877-6884(2009)
Ramakrishnan, N.A., et al. J. Biol. Chem. 284(3):1364-1372(2009)
Tian, J.H., et al. J. Biol. Chem. 278(28):26265-26274(2003)

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$ 295.00
$ 99.00
Cat# AP9813a
(40 western blots)
Availability: In Stock
Bulk Size
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