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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   BSND Antibody (C-term)   

BSND Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - BSND Antibody (C-term) AP9858b
    Western blot analysis of BSND Antibody (C-term) (Cat. #AP9858b) in mouse liver tissue lysates (35ug/lane). BSND (arrow) was detected using the purified Pab.
  • IHC-P - BSND Antibody (C-term) AP9858b
    BSND Antibody (C-term) (Cat. #AP9858b) IHC analysis in formalin fixed and paraffin embedded mouse kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BSND Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WZ55
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35197 Da
Antigen Region 292-320 aa
Additional Information
Gene ID 7809
Other Names Barttin, BSND, BART
Target/Specificity This BSND antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-320 amino acids from the C-terminal region of human BSND.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBSND Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BART
Function Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral (By similarity).
Tissue Location Expressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear.
Research Areas
Citations (0)

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BSND encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear.


Riazuddin, S., et al. Am. J. Hum. Genet. 85(2):273-280(2009)
Brochard, K., et al. Nephrol. Dial. Transplant. 24(5):1455-1464(2009)
Bircan, Z., et al. Pediatr. Nephrol. 24(4):841-844(2009)
Kathiresan, S., et al. Nat. Genet. 41(3):334-341(2009)
Kathiresan, S., et al. Nat. Genet. 41(1):56-65(2009)

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$ 295.00
$ 99.00
Cat# AP9858b
(40 western blots)
Availability: In Stock
Bulk Size
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