|Application ||WB, IHC-P, FC, E|
|Calculated MW||25497 Da|
|Antigen Region||93-120 aa|
|Other Names||Glutathione S-transferase kappa 1, GST 13-13, GST class-kappa, GSTK1-1, hGSTK1, Glutathione S-transferase subunit 13, GSTK1|
|Target/Specificity||This GSTK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the Central region of human GSTK1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GSTK1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).|
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Provided below are standard protocols that you may find useful for product applications.
GSTK1 encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.
Santos, G.S., et al. Int. J. Mol. Med. 24(3):393-399(2009)
Aydos, S.E., et al. Fertil. Steril. 92(2):541-547(2009)
Gao, F., et al. Endocr. J. 56(3):487-494(2009)
Katoh, T., et al. Pharmacogenomics 9(1):93-104(2008)
Li, J., et al. Protein Sci. 14(9):2361-2369(2005)
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