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Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UBP6 |
| Other Accession | Q9Z120, Q2YDF1 |
| Reactivity | Human |
| Predicted | Bovine, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Calculated MW | 31471 Da |
| Antigen Region | 147-175 aa |
| Gene ID | 4234 |
|---|---|
| Other Names | tRNA (guanine-N(7)-)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}, 21133 {ECO:0000255|HAMAP-Rule:MF_03055}, Methyltransferase-like protein 1 {ECO:0000255|HAMAP-Rule:MF_03055}, tRNA (guanine(46)-N(7))-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}, tRNA(m7G46)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}, METTL1 {ECO:0000255|HAMAP-Rule:MF_03055}, C12orf1 |
| Target/Specificity | This METTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human METTL1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | METTL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | METTL1 {ECO:0000255|HAMAP-Rule:MF_03055} |
|---|---|
| Synonyms | C12orf1 |
| Function | Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. |
| Cellular Location | Nucleus {ECO:0000255|HAMAP-Rule:MF_03055, ECO:0000269|PubMed:15861136} |
| Tissue Location | Ubiquitous.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.
References
Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
Nat. Genet. 41(7):824-828(2009)
Cartlidge, R.A., et al. EMBO J. 24(9):1696-1705(2005)
Alexandrov, A., et al. RNA 8(10):1253-1266(2002)
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