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METTL1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - METTL1 Antibody (Center) AP9887c
    Western blot analysis of METTL1 Antibody (Center) (Cat. #AP9887c) in Ramos cell line lysates (35ug/lane). METTL1 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBP6
Other Accession Q9Z120, Q2YDF1
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 31471 Da
Antigen Region 147-175 aa
Additional Information
Gene ID 4234
Other Names tRNA (guanine-N(7)-)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}, 21133 {ECO:0000255|HAMAP-Rule:MF_03055}, Methyltransferase-like protein 1 {ECO:0000255|HAMAP-Rule:MF_03055}, tRNA (guanine(46)-N(7))-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}, tRNA(m7G46)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}, METTL1 {ECO:0000255|HAMAP-Rule:MF_03055}, C12orf1
Target/Specificity This METTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human METTL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMETTL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name METTL1 {ECO:0000255|HAMAP-Rule:MF_03055}
Synonyms C12orf1
Function Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
Cellular Location Nucleus {ECO:0000255|HAMAP-Rule:MF_03055, ECO:0000269|PubMed:15861136}
Tissue Location Ubiquitous..
Citations (0)

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This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.


Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
Nat. Genet. 41(7):824-828(2009)
Cartlidge, R.A., et al. EMBO J. 24(9):1696-1705(2005)
Alexandrov, A., et al. RNA 8(10):1253-1266(2002)

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$ 295.00
$ 99.00
Cat# AP9887c
(40 western blots)
Availability: In Stock
Bulk Size
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