METTL1 Antibody (Center)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, E |
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Primary Accession | Q9UBP6 |
Other Accession | Q9Z120, Q2YDF1 |
Reactivity | Human |
Predicted | Bovine, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit Ig |
Calculated MW | 31471 Da |
Antigen Region | 147-175 aa |
Gene ID | 4234 |
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Other Names | tRNA (guanine-N(7)-)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}, 21133 {ECO:0000255|HAMAP-Rule:MF_03055}, Methyltransferase-like protein 1 {ECO:0000255|HAMAP-Rule:MF_03055}, tRNA (guanine(46)-N(7))-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}, tRNA(m7G46)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}, METTL1 {ECO:0000255|HAMAP-Rule:MF_03055}, C12orf1 |
Target/Specificity | This METTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human METTL1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | METTL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | METTL1 {ECO:0000255|HAMAP-Rule:MF_03055} |
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Synonyms | C12orf1 |
Function | Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. |
Cellular Location | Nucleus {ECO:0000255|HAMAP-Rule:MF_03055, ECO:0000269|PubMed:15861136} |
Tissue Location | Ubiquitous.. |

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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.
References
Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
Nat. Genet. 41(7):824-828(2009)
Cartlidge, R.A., et al. EMBO J. 24(9):1696-1705(2005)
Alexandrov, A., et al. RNA 8(10):1253-1266(2002)

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