- CITATIONS: 2
|Application ||WB, FC, E|
|Calculated MW||72049 Da|
|Antigen Region||613-641 aa|
|Other Names||Protein THEMIS2, Induced by contact to basement membrane 1 protein, Protein ICB-1, Thymocyte-expressed molecule involved in selection protein 2, THEMIS2, C1orf38, ICB1|
|Target/Specificity||This ICB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the C-terminal region of human ICB1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ICB1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May constitute a control point in macrophage inflammatory response, promoting LPS-induced TNF production.|
|Tissue Location||Expressed in different endometrial adenocarcinoma cell lines and various other cell lines apart from the prostate cell line LNCaP and the ovarian cancer cell line BG1|
Provided below are standard protocols that you may find useful for product applications.
Involved in cell adhesion. There are 4 isoforms produced by alternative splicing.
Springwald, A., et al. Cancer Invest. 27(6):669-672(2009)
Treeck, O., et al. Cytokine 32 (3-4), 137-142 (2005)
Treeck, O., et al. Leuk. Res. 26(8):765-769(2002)
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