|Application ||WB, IHC-P, FC, E|
|Other Accession||P11654, Q9QY81|
|Calculated MW||205111 Da|
|Antigen Region||202-231 aa|
|Other Names||Nuclear pore membrane glycoprotein 210, Nuclear pore protein gp210, Nuclear envelope pore membrane protein POM 210, POM210, Nucleoporin Nup210, Pore membrane protein of 210 kDa, NUP210, KIAA0906|
|Target/Specificity||This NUP210 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-231 amino acids from the N-terminal region of human NUP210.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NUP210 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity.|
|Cellular Location||Nucleus, nuclear pore complex. Nucleus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein|
|Tissue Location||Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
NUP210 nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex.
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Stavru, F., et al. J. Cell Biol. 173(4):477-483(2006)
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