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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ELOVL5 Antibody (C-term)   

ELOVL5 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ELOVL5 Antibody (C-term) AP9968a
    Western blot analysis of ELOVL5 Antibody (C-term) (Cat. #AP9968a) in Hela cell line lysates (35ug/lane). ELOVL5 (arrow) was detected using the purified Pab.
  • FC - ELOVL5 Antibody (C-term) AP9968a
    ELOVL5 Antibody (C-term) (Cat. #AP9968a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NYP7
Other Accession Q4R516
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35293 Da
Antigen Region 271-299 aa
Additional Information
Gene ID 60481
Other Names Elongation of very long chain fatty acids protein 5, 3-keto acyl-CoA synthase ELOVL5, ELOVL fatty acid elongase 5, ELOVL FA elongase 5, Fatty acid elongase 1, hELO1, Very-long-chain 3-oxoacyl-CoA synthase 5, ELOVL5, ELOVL2
Target/Specificity This ELOVL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-299 amino acids from the C-terminal region of human ELOVL5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsELOVL5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ELOVL2
Function Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree
Tissue Location Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain Expressed in the cerebellum.
Research Areas
Citations (0)

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ELOVL5 plays a role in elongation of long-chain polyunsaturated fatty acids.


Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Barragan, I., et al. Int. J. Mol. Med. 16(6):1163-1167(2005)

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Cat# AP9968a
(40 western blots)
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