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TLR11 Antibody

  • WB - TLR11 Antibody ASC10233
    Western blot analysis of TLR11 in RAW264.7 cell lysates with TLR11 antibody at (A) 0.5 and (B) 1 µg/mL.
  • ICC - TLR11 Antibody ASC10233
    Immunocytochemical staining of RAW264.7 cells using TLR11 antibody at 2 µg/mL.
  • IF - TLR11 Antibody ASC10233
    Immunofluorescence of TLR11 in Raw264.7 cells with TLR11 antibody at 10 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6R5P0
Other Accession NP_991388, 45429992
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 105873 Da
Application Notes TLR11 antibody can be used for detection of TLR11 by Western blot at 0.5 to 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2 µg/mL. For immunofluorescence start at 10 µg/mL.
Additional Information
Gene ID 239081
Other Names TLR11 Antibody: Gm287, Gm287, Toll-like receptor 11, toll-like receptor 11
Target/Specificity Tlr11;
Reconstitution & Storage TLR11 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsTLR11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tlr11
Synonyms Gm287
Function Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Citations (0)

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TLR11 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.


Vogel SN, Fitzgerald KA, and Fenton MJ. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 2003; 3:466-77.
Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.
Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002; 20:197-216.
O’Neill LAJ, Fitzgerald FA, and Bowie AG. The Toll-IL-1 receptor adaptor family grows to five members. Trends in Imm. 2003; 24:286-9.

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$ 310.00
Cat# ASC10233
(40 western blots)
Availability: 5-7days
Bulk Size
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