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Rim3 Antibody

  • WB - Rim3 Antibody ASC10642
    Western blot analysis of Rim3 in human brain tissue lysate with Rim3 antibody at 1 µg/mL in the (A) absence and (B) presence of blocking peptide.
  • IHC - Rim3 Antibody ASC10642
    Immunohistochemistry of Rim3 in human brain tissue with Rim3 antibody at 2.5 µg/mL.
  • IF - Rim3 Antibody ASC10642
    Immunofluorescence of rim3 in human brain tissue with rim3 antibody at 5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UJD0
Other Accession NP_055562, 48476344
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 32796 Da
Application Notes Rim3 antibody can be used for detection of Rim3 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 5 µg/mL.
Additional Information
Gene ID 9783
Target/Specificity RIMS3; This antibody is predicted to have no cross-reactivity to other Rim proteins.
Reconstitution & Storage Rim3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsRim3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RIMS3
Synonyms KIAA0237
Function Regulates synaptic membrane exocytosis.
Cellular Location Cell junction, synapse.
Research Areas
Citations (0)

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Rim3 Antibody: Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.


Wang Y, Sugita S, and Sudhof TC. The RIM/NIM family of neuronal C2 domain proteins: interactions with Rab3 and a new class of Src homology 3 domain proteins. J. Biol. Chem.2000; 275:20033-44.
Liang F, Zhang B, Tang J, et al. RIM3gamma is a postsynaptic protein in the rat central nervous system. J. Comp. Neurol.2007; 503:501-10.

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$ 310.00
Cat# ASC10642
(40 western blots)
Availability: 5-7days
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