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GRTP1 Antibody

  • WB - GRTP1 Antibody ASC10686
    Western blot analysis of GRTP1 in SK-N-SH cell lysate with GRTP1 antibody at 1 µg/mL in the (A) absence and (B) presence of blocking peptide.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5TC63
Other Accession EAX09206, 119629611
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 38554 Da
Application Notes GRTP1 antibody can be used for detection of GRTP1 by Western blot at 1 µg/mL.
Additional Information
Gene ID 79774
Target/Specificity GRTP1; At least three isoforms of GRTP1 are known to exist; this antibody should recognize all isoforms.
Reconstitution & Storage GRTP1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsGRTP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRTP1
Synonyms TBC1D6
Function May act as a GTPase-activating protein for Rab family protein(s).
Research Areas
Citations (0)

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GRTP1 Antibody: Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment.


Lu C, Kasik J, Stephan DA, et al. Grtp1, a novel gene regulated by growth hormone. Endocriniology2001; 142:4568-71.
Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science2008; 319:921-6.

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$ 310.00
Cat# ASC10686
(40 western blots)
Availability: 5-7days
Bulk Size
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