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KLRA3 Antibody

  • WB - KLRA3 Antibody ASC10836
    Western blot analysis of KLRA3 in mouse brain tissue lysate with KLRA3 antibody at 2 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q64329
Other Accession AAI32525, 124376782
Reactivity Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 31311 Da
Application Notes KLRA3 antibody can be used for detection of KLRA3 by Western blot at 2 µg/mL.
Additional Information
Gene ID 16634
Target/Specificity Klra3; This antibody may cross-react with other LY49 receptors.
Reconstitution & Storage KLRA3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsKLRA3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Klra3
Synonyms Ly-49c, Ly49C
Function Receptor on natural killer (NK) cells for class I MHC.
Cellular Location Membrane; Single-pass type II membrane protein
Citations (0)

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KLRA3 Antibody: KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.


Gosselin P, Lusignan Y, Brennan J, et al. The NK2.1 receptor is encoded by Ly-49C and its expression is regulated by MHC class I alleles. Int. Immunol.1997; 533-40.
Smith HR, Karlhofer FM, and Yokoyama WM. Ly-49 multigene family expressed by IL-2-activated NK cells. J. Immunol.1994; 153:1068-79.
Brennan J, Mager D, Jefferies W, et al. Expression of different members of the Ly-49 gene family defines distinct natural killer cell subsets and cell adhesion properties. J. Exp. Med.1994; 180:2287-95.
Su R-C, Kung SK, Silver ET, et al. Ly-49CB6 NK inhibitory receptor recognizes peptide-receptive H-2Kb. J. Immunol.1999; 163:5319-30.

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$ 310.00
Cat# ASC10836
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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