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FRMPD3 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q5JV73 |
| Other Accession | Q5JV73, 118582027 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 195652 Da |
| Application Notes | FRMPD3 antibody can be used for detection of FRMPD3 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL. |
| Gene ID | 84443 |
|---|---|
| Target/Specificity | FRMPD3; |
| Reconstitution & Storage | FRMPD3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | FRMPD3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FRMPD3 (HGNC:29382) |
|---|---|
| Synonyms | KIAA1817 |
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Provided below are standard protocols that you may find useful for product applications.
Background
FRMPD3 Antibody: The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. Unlike other members of the FRMPD family, FRMPD3 has no known function. It is most similar to FRMPD4, which is highly expressed in multiple regions of the brain and enriched in the postsynaptic density (PSD) fractions, it is possible that FRMPD3 also interacts with other PDZ domain-containing proteins in neural cells.
References
An N, Blumer JB, Bernard ML. The PDZ and Band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins. J. Biol. Chem.2008; 283:24718-28.
Stenzel N, Fetzer CP, Heumann R, et al. PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells. J. Cell Sci.2009; 122:3374-84.
Lee HW, Choi J, Shin H, et al. Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis. J. Neurosci.2008; 28:14546-56.
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