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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   FAM212A Antibody   

FAM212A Antibody

  • WB - FAM212A Antibody ASC11035
    Western blot analysis of FAM212A in EL4 cell lysate with FAM212A antibody at (A) 1 and (B) 2 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96EL1
Other Accession NP_976248, 42766424
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 32 kDa

Observed: 33 kDa
Application Notes FAM212A antibody can be used for detection of FAM212A by Western blot at 1 - 2 µg/ml.
Additional Information
Gene ID 389119
Target/Specificity FAM212A; FAM212A antibody is human and mouse . At least two isoforms of FAM212A are known to exist; this antibody will recognize both isoforms.
Reconstitution & Storage FAM212A antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsFAM212A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FAM212A (HGNC:32480)
Function Inhibitor of the serine/threonine-protein kinase PAK4 (PubMed:26607847). Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity (PubMed:26607847).
Cellular Location Nucleus. Cytoplasm. Note=Mainly nuclear (PubMed:26607847). Relocalizes to the cytoplasm following interaction with PAK4 (PubMed:26607847)
Research Areas
Citations (0)

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FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives (1). FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics (1). In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly (2).


Luo T, Xu Y, Hoffman TL, et al. Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Dev. 2007; 134:1279-89.
Reid BS, Sargent TD, and Willams T. Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure. Dev. Dyn. 2010; 239:1188-96.

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$ 330.00
Cat# ASC11035
Availability: 5-7days
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