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REEP2 Antibody

     
  • WB - REEP2 Antibody ASC11050
    Western blot analysis of REEP2 in mouse lung tissue lysate with REEP2 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
    detail
  • IHC - REEP2 Antibody ASC11050
    Immunohistochemistry of REEP2 in rat lung tissue with REEP2 antibody at 5 µg/mL.
    detail
  • IF - REEP2 Antibody ASC11050
    Immunofluorescence of REEP2 in rat lung tissue with REEP2 antibody at 20 µg/mL.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q9BRK0
Other Accession EAW62139, 119582543
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 28261 Da
Application Notes REEP2 antibody can be used for detection of REEP2 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 51308
Target/Specificity REEP2;
Reconstitution & Storage REEP2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsREEP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name REEP2
Synonyms C5orf19, SGC32445
Function Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors (By similarity).
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Detected in brain, heart and skeletal muscle, and at low levels in placenta, kidney and pancreas (PubMed:11161817) Expressed in circumvallate papillae (PubMed:16720576)
Research Areas
Citations (0)
citation

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Background

REEP2 Antibody: Mammalian odorant receptors require accessory proteins such as RTP1 and RTP2 for functional cell surface expression. Receptor expression-enhancing protein (REEP) family members are transmembrane proteins which interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. Recently studies have shown other chemosensory receptors such as bitter taste receptors are also influenced by RTP and REEP family members.

References

Saito H, Kubota M, Roberts RW, et al. RTP family members induce functional expression of mammalian odorant receptors. Cell2004; 119:679-91.
Behrens M, Bartelt J, Reichling et al. Members of RTP and REEP gene families influence functional bitter taste receptor expression. J. Biol. Chem.2006; 281:20650-9.

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$ 379.00
Cat# ASC11050
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