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SCUBE2 Antibody

  • WB - SCUBE2 Antibody ASC11166
    Western blot analysis of SCUBE2 in Daudi cell lysate with SCUBE2 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • ICC - SCUBE2 Antibody ASC11166
    Immunocytochemistry of SCUBE2 in Daudi cells with SCUBE2 antibody at 20 µg/mL.
  • IF - SCUBE2 Antibody ASC11166
    Immunofluorescence of SCUBE2 in Daudi cells with SCUBE2 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NQ36
Other Accession NP_066025, 283046663
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 109966 Da
Application Notes SCUBE2 antibody can be used for detection of SCUBE2 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 20 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 57758
Target/Specificity SCUBE2;
Reconstitution & Storage SCUBE2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsSCUBE2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CEGP1
Cellular Location Secreted.
Tissue Location Expressed in a broad spectrum of adult tissues.
Research Areas
Citations (0)

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SCUBE2 Antibody: SCUBE2 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and are expressed in embryonic neuroectoderm and vascular epithelium. SCUBE2 is a close homolog to SCUBE1 and can form a heterodimeric complex with SCUBE1. SCUBE2 is thought to participate in the Hedgehog signaling pathway by specifically interacting with Sonic Hedgehog (SHH) and the receptor PTCH1, enhancing the SHH signaling activity in the raft microdomains of the plasma membrane, and may thus play important roles in organ development and tumor progression.


Grimmond S, Larder R, Van Hateren N, et al. Cloning, mapping, and expression analysis of a gene encoding a novel mammalian EGF-related protein (SCUBE1). Genomics2000; 70:74-81.
Yang RB, Ng CK, Wasserman SM, et al. Identification of a novel family of cell-surface proteins expressed in human vascular endothelium. J. Biol. Chem.2002; 277:46364-73.
Grimmond S, Larder R, Van Hateren N, et al. Cloning, mapping, and expression analysis of a gene encoding a novel mammalian EGF-related protein (SCUBE1). Genomics2000; 70:74-81.
Tsai M, Cheng C, Lin Y, et al. Isolation and characterization of a secreted, cell-surface glycoprotein SCUBE2 from humans. Biochem. J. 2009; 422:119-28.

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$ 310.00
Cat# ASC11166
(40 western blots)
Availability: 5-7days
Bulk Size
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