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SYNPO2L Antibody

  • WB - SYNPO2L Antibody ASC11236
    Western blot analysis of SYNPO2L in human thymus tissue lysate with SYNPO2L antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • IHC - SYNPO2L Antibody ASC11236
    Immunohistochemistry of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 5 µg/mL.
  • IF - SYNPO2L Antibody ASC11236
    Immunofluorescence of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H987
Other Accession BAD37139, 51534920
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 102481 Da
Application Notes SYNPO2L antibody can be used for detection of SYNPO2L by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 79933
Target/Specificity SYNPO2L;
Reconstitution & Storage SYNPO2L antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsSYNPO2L Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Actin-associated protein that may play a role in modulating actin-based shape.
Cellular Location Cytoplasm, cytoskeleton.
Research Areas
Citations (0)

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SYNPO2L Antibody: SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.


Beqqali A, Kloots J, Ward-van Oostward D, et al. Genome-wide transcriptional profiling of human embryonic stem cells differentiating to cardiomyocytes. Stem Cells2006; 24:1956-67.
Beqqali A, Manshouwer-Kloots J, Moneiro R, et al. CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function. J. Cell Sci.2010; 123:1141-50.

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$ 310.00
Cat# ASC11236
(40 western blots)
Availability: 5-7days
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