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SHISA9 Antibody

  • WB - SHISA9 Antibody ASC11238
    Western blot analysis of SHISA9 in rat brain tissue lysate with SHISA9 antibody at 1 µg/mL.
  • IHC - SHISA9 Antibody ASC11238
    Immunohistochemistry of SHISA9 in human brain tissue with SHISA9 antibody at 2.5 µg/mL.
  • IF - SHISA9 Antibody ASC11238
    Immunofluorescence of SHISA9 in human brain tissue with SHISA9 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession B4DS77
Other Accession NP_001138676, 291463300
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 46925 Da
Application Notes SHISA9 antibody can be used for detection of SHISA9 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 729993
Target/Specificity SHISA9;
Reconstitution & Storage SHISA9 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsSHISA9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity).
Cellular Location Cell projection, dendritic spine membrane; Single-pass type I membrane protein Cell junction, synapse
Research Areas
Citations (0)

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SHISA9 Antibody: Shisa proteins are a recently-identified family of modulators of both FGF and Wnt signaling that block both maturation and transport to the cell surface of their respective receptors. SHISA9, also known as CKAMP44a, is a brain-specific type I transmembrane protein that associates with AMPA receptors in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses. It is thought to modulate short-term plasticity at specific excitatory synapses.


Hedge TA and Mason I. Expression of Shisa2, a modulator of both Wnt and Fgf signaling, in the chick embryo. Int. J. Dev. Biol.2008; 52:81-5.
Von Engelhardt J, Mack V, Sprengel R, et al. CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus. Science2010; 327:1518-22.
O'Donovan MC, Craddock N, Norton N, et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat. Genet.2008; 40:1053-5.

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$ 310.00
Cat# ASC11238
(40 western blots)
Availability: 5-7days
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