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SLAMF2 Antibody

  • WB - SLAMF2 Antibody ASC11304
    Western blot analysis of SLAMF2 in rat lung tissue lysate with SLAMF2 antibody at (A) 1 and (B) 2 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09326
Other Accession NP_1769, 21361571
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 27683 Da
Application Notes SLAMF2 antibody can be used for detection of SLAMF2 by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 962
Target/Specificity CD48; Two isoforms of SLAMF2 are known to exist; this antibody will recognize both isoforms. SLAMF2 antibody is predicted to not cross-react with other SLAM protein family members.
Reconstitution & Storage SLAMF2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsSLAMF2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD48
Synonyms BCM1, BLAST1
Function Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor
Research Areas
Citations (0)

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SLAMF2 Antibody: The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.


Smith GM, Biggs J, Norris B, et al. Detection of a soluble form of the leukocyte surface antigen CD48 in plasma and its elevation in patients with lymphoid leukemias and arthritis. J. Clin. Immunol. 1997; 17:502-9.
Sidorenko SP and Clark EA. The dual-function CD150 receptor sub-family: the viral attraction. Nat. Immunol. 4:19-24.
Munitz A, Bachelot I, Eliashar R, et al. CD48 is an allergen and IL-3-induced activation molecule on eosinophils. J. Immunol. 2006; 177:77-83.
Fukushima K, Ikehara Y, and Yamashita K. Functional role played by the glycosylphosphatidylinositol anchor glycan of CD48 in interleukin-18-induced interferon-gamma production. J. Biol. Chem. 2005; 280:18056-62.

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$ 330.00
Cat# ASC11304
Availability: 5-7days
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