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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Paralemmin3 Antibody   

Paralemmin3 Antibody

  • WB - Paralemmin3 Antibody ASC11363
    Western blot analysis of Paralemmin3 in MCF7 cell lysate with Paralemmin3 antibody at 1 µg/mL.
  • ICC - Paralemmin3 Antibody ASC11363
    Immunocytochemistry of Paralemmin 3 in MCF7 cells with Paralemmin 3 antibody at 5 µg/mL.
  • IF - Paralemmin3 Antibody ASC11363
    Immunofluorescence of Paralemmin 3 in MCF7 cells with Paralemmin 3 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession A6NDB9
Other Accession NP_001138500, 222537747
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 71695 Da
Application Notes Paralemmin3 antibody can be used for detection of Paralemmin3 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 342979
Target/Specificity PALM3; At least two isoforms of Paralemmin3 are known to exist; this antibody will only detect the longer isoform
Reconstitution & Storage Paralemmin3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsParalemmin3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PALM3
Function ATP-binding protein, which may act as a adapter in the Toll-like receptor (TLR) signaling.
Cellular Location Cytoplasm. Cell membrane; Lipid-anchor
Research Areas
Citations (0)

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Paralemmin3 Antibody: Paralemmin3 is a recently identified protein that associates with the single immunoglobulin IL-1 receptor-related molecule (SIGIRR), a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Silencing of Paralemmin3 expression by RNAi inhibited the release of inflammatory cytokines in A549 cells after stimulation with lipopolysaccharide (LPS), suggesting Paralemmin3 may function as an adaptor in the LPS-TLR4 signaling pathway.


Chen X, Wu X, Zhao Y, et al. A novel binding protein of single immunoglobulin IL-1 receptor-related molecule: Paralemmin-3. Biochem. Biophys. Res. Commun. 2011; 404:1029-33
Wald D, Qin J, Zhao Z, et al. SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Nat. Immunol. 2003; 4:920-7.

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$ 310.00
Cat# ASC11363
(40 western blots)
Availability: 5-7days
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