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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   UHRF1BP1 Antibody   

UHRF1BP1 Antibody

  • WB - UHRF1BP1 Antibody ASC11367
    Western blot analysis of UHRF1BP1 in mouse kidney tissue lysate with UHRF1BP1 antibody at (A) 1 and (B) 2 µg/mL.
  • IHC - UHRF1BP1 Antibody ASC11367
    Immunohistochemistry of UHRF1BP1 in human kidney tissue with UHRF1BP1 antibody at 2.5 µg/mL.
  • IF - UHRF1BP1 Antibody ASC11367
    Immunofluorescence of UHRF1BP1 in human kidney tissue with UHRF1BP1 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6BDS2
Other Accession NP_060224, 134152667
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 159485 Da
Application Notes UHRF1BP1 antibody can be used for detection of UHRF1BP1 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 54887
Target/Specificity UHRF1BP1; UHRF1BP1 antibody is predicted to not cross-react with UHRF1BP1L
Reconstitution & Storage UHRF1BP1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsUHRF1BP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C6orf107
Function May act as a negative regulator of cell growth.
Research Areas
Citations (0)

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UHRF1BP1 Antibody: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.


Hopfner R, Mousli M, Jeltsch JM, et al. ICBP90, a novel human CCAAT binding protein, involved in the regulation of Topoisomerase IIα expression. Cancer Res. 2000; 60:121-8
Unoki M, Nishidate T and Nakamura Y. ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain. Oncogene 2004; 23:7601-10.
Karagianni P, Amazit L, Qin J, et al. ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation. Mol. Cell Biol. 2008; 28:705-17.
Fang Z, Xing F, Bronner C, et al. ICBP90 mediates the ERK1/2 signaling to regulate the proliferation of Jurkat T cells. Cell Immunol. 2009; 257:80-7.

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$ 310.00
Cat# ASC11367
(40 western blots)
Availability: 5-7days
Bulk Size
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