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NKX2-8 Antibody

  • WB - NKX2-8 Antibody ASC11449
    Western blot analysis of NKX2-8 in rat liver tissue lysate with NKX2-8 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide
  • IHC - NKX2-8 Antibody ASC11449
    Immunohistochemistry of NKX2-8 in human liver tissue with NKX2-8 antibody at 2.5 µg/mL.
  • IF - NKX2-8 Antibody ASC11449
    Immunofluorescence of NKX-8 in human liver tissue with NKX2-8 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15522
Other Accession NP_055175, 31377777
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 25866 Da
Application Notes NKX2-8 antibody can be used for detection of NKX2-8 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 2.5 µg/mL.
Additional Information
Gene ID 26257
Target/Specificity NKX2-8; NKX2-8 antibody is predicted to not cross-react with other NK2 homeobox family members.
Reconstitution & Storage NKX2-8 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsNKX2-8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NKX2-8
Synonyms NKX-2.8, NKX2G, NKX2H
Cellular Location Nucleus.
Citations (0)

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NKX2-8 Antibody: NKX2-8 (NK2 homeobox 8) is a member of a family of transcription factors that are involved in embryonic development and cell fate. It is expressed in the ventral foregut, the developing heart, the epithelial layers of the branchial arches and in the dorsal mesoderm. In conjunction with related protein, NKX2-5, NKX2-8 may play a role in cardiac embryonic development. NKX2-8 is also thought to be involved in lung development and is suspected of being an oncogene in lung cancer that is activated by way of gene amplification at chromosome 14q13.


Boettger T, Stein S, and Kessel M. The chicken NKX2.8 homeobox gene: A novel member of the NK-2 gene family. Dev. Genes Evol. 1997; 207:65-70.
Kendall J, Liu Q, Bakleh A, et al. Oncogenic ccooperation and coamplification of developmental transcription factor genes in lung cancer. Proc. Natl. Acad. Sci. USA 2007; 104:16663-8.
Hsu DS, Acharya CR, Balakumaran BS, et al. Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer. Proc. Natl. Acad. Sci. USA 2009; 106:5312-7.

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$ 310.00
Cat# ASC11449
Availability: 5-7days
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