|Application ||WB, IHC-P, IF, E|
|Other Accession||NP_057192, 40316941|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||28222 Da|
|Application Notes||AIG1 antibody can be used for detection of AIG1 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 2.5 µg/mL.|
|Reconstitution & Storage||AIG1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.|
|Precautions||AIG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in androgen-regulated growth of hair follicles.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Highly expressed in heart, ovary, testis, liver, and kidney, at lower levels in spleen, prostate, brain, skeletal muscle, pancreas, small intestine and colon, and undetected in peripheral blood leukocytes, thymus, lung and placenta. AIG1 expression is higher in hair follicles from males than from females.|
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Provided below are standard protocols that you may find useful for product applications.
AIG1 Antibody: Androgen-induced 1 (AIG1) is a novel Pirh2-interacting protein, which was initially cloned from human dermal papilla cells and is evolutionally conserved from drosophila through to humans. It is a membrane protein and belongs to the protein family containing FAR-17a domain. AIG1 may play a role in androgen-regulated growth of hair follicles. AIG1 could serve as a new biomarker for the diagnosis and prognostic evaluation of HCCs and may be a novel candidate tumor suppressor.
Wu G, Sun M, Zhang W, et al. AIG1 is a novel Pirh2-interacting protein that activates the NFAT signaling pathway. Front. Biosci. (Elite Ed). 2011; 3:834-42.
Seo J, Kim J, and Kim M. Cloning of androgen-inducible gene 1 (AIG1) from human dermal papilla cells. Mol. Cells 2001; 11:35-40.
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