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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PTPRD Antibody   

PTPRD Antibody

  • WB - PTPRD Antibody ASC11490
    Western blot analysis of PTPRD in HeLa cell lysate with PTPRD antibody at 1 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23468
Other Accession NP_569075, 289547551
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 165, 210 kDa (130 kDa for cleavage product)

Observed: 130 kDa
Application Notes PTPRD antibody can be used for detection of PTPRD by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 5789
Target/Specificity PTPRD; PTPRD antibody is human specific. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. PTPRD cleavage products are often observed in vivo
Reconstitution & Storage PTPRD antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsPTPRD Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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PTPRD Antibody: PTPRD (Protein tyrosine phosphatase receptor type D) is a member of the protein tyrosine phosphatase (PTP) family that plays diverse roles during development including cell growth, differentiation, mitotic cycle and oncogenic transformation. PTPRD contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. The extracellular region of PTPRD is composed of three Ig-like and eight fibronectin type III-like domains (1,3). PTPRD interacts with PPFIA1-3 and is a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiforme (GBMs) and multiple human cancers.


Krueger NX, Streuli M, and Saito H. Structural diversity and evolution of human receptor-like protein tyrosine phosphatases. EMBO J. 1990; 9:3241-52.
Fischer EH, Charbonneau H and Tonks NK. Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes. Science 1991; 253:401-6.
Pan MG, Rim C, Lu KP et al. Cloning and expression of two structurally distinct receptor-linked protein-tyrosine phosphatases generated by RNA processing from a single gene. J. Biol. Chem. 1993; 268:19284-91.
Veeriah S, Brennan C, Meng S, et al. The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers. Proc. Natl. Acad. Sci. USA 2009; 106: 9435-40.

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$ 310.00
Cat# ASC11490
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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