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SEPT1 Antibody

  • WB - SEPT1 Antibody ASC11497
    Western blot analysis of SEPT1 in Raji cell lysate with SEPT1 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
  • ICC - SEPT1 Antibody ASC11497
    Immunocytochemistry of SEPT1 in Raji cells with SEPT1 antibody at 5 µg/mL.
  • IF - SEPT1 Antibody ASC11497
    Immunofluorescence of SEPT1 in Raji cells with SEPT1 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WYJ6
Other Accession NP_443070, 431822382
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 41971 Da
Application Notes SEPT1 antibody can be used for detection of SEPT1 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 5 µg/mL. For immunofluorescence start at 5 µg/mL.
Additional Information
Gene ID 1731
Target/Specificity SEPT1; At least two isoforms of SEPT1 are known to exist. This antibody is predicted to not cross-react with other Septin protein family members.
Reconstitution & Storage SEPT1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsSEPT1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEPT1
Synonyms DIFF6, PNUTL3
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis Localizes to the midbody during cytokinesis
Tissue Location Expressed at high levels in lymphoid and hematopoietic tissues.
Research Areas
Citations (0)

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SEPT1 Antibody: SEPT1 (also known as Septin 1), is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. SEPT1 was initially identified through yeast two-hybrid screening as an interaction partner for the serine/threonine kinase Aurora-B. During mitosis, SEPT1 localizes to the spindle pole, suggesting that it may play a role in cytokinesis and chromosome congression.


Qi M, Yu W, Liu S, et al. Septin1, a new interaction partner for human serine/threonine kinase aurora-B. Biochem. Biophys. Res. Commun. 2005; 336:994-1000.
Russell SE and Hall PA. Septin genomics: a road less travelled. Biol. Chem. 2011; 392:763-7.
Zhu J, Qi ST, Wang YP, et al. Septin1 is required for spindle assembly and chromosome congression in mouse oocytes. Dev. Dyn. 2011; 240:2281-9.

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$ 310.00
Cat# ASC11497
(40 western blots)
Availability: 5-7days
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