|Application ||WB, IF, E|
|Other Accession||NP_115873, 14210490|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||58 kDa|
|Application Notes||GHDC antibody can be used for detection of GHDC by Western blot at 0.5 - 1 µg/mL. For immunofluorescence start at 20 µg/mL.|
|Target/Specificity||GHDC; Multiple isoforms are known to exist.|
|Reconstitution & Storage||GHDC antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.|
|Precautions||GHDC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Endoplasmic reticulum. Nucleus envelope|
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Provided below are standard protocols that you may find useful for product applications.
GHDC Antibody: GHDC, also known as LGP1, is a GH3 domain-containing protein that is highly expressed in normal mammary tissues and mammary tumors. GHDC is primarily located in the nuclear envelope. In mouse, its gene is located on chromosome 11 adjacent to the STAT3/5 locus. Little is known of the function of this protein.
Cui Y, Li M, Walton KD, et al. The Stat3/5 locus encodes novel endoplasmic reticulum and helicase-like proteins that are preferentially expressed in normal and neoplastic mammary tissue. Genomics 2001; 78:129-34.
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