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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   CCL17 Antibody   

CCL17 Antibody

  • WB - CCL17 Antibody ASC11619
    Western blot analysis of CCL17 in rat spleen tissue lysate with CCL17 antibody at (A) 1 and (B) 2 µg/mL
  • IHC - CCL17 Antibody ASC11619
    Immunohistochemistry of CCL17 in spleen tissue with CCL17 antibody at 5 µg/ml.
  • IF - CCL17 Antibody ASC11619
    Immunofluorescence of CCL17 in human spleen tissue with CCL17 antibody at 20 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92583
Other Accession NP_002978, 4506829
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 10 kDa
Application Notes CCL17 antibody can be used for detection of CCL17 by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 6361
Target/Specificity CCL17;
Reconstitution & Storage CCL17 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsCCL17 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCL17
Synonyms SCYA17, TARC
Function Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.
Cellular Location Secreted.
Tissue Location Expressed at high levels in thymus and at low levels in the lung, colon and small intestine
Research Areas
Citations (0)

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CCL17 Antibody: CCL17, also known as TARC, binds to chemokine receptors CCR4 and CCR8 and plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 is secreted from monocyte-derived DCs and endothelial cells and is responsible for selective recruitment and migration of activated Th2 lymphocytes. CCL17 is also required for CCR7 and CXCR4-dependent migration of cutaneous dendritic cells under inflammatory conditions.


Imai T, Baba M, Nishimura M, et al. The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J. Biol. Chem. 1997; 272:15036-42.
Bernardini G, Hedrick J, Sozzani S, et al. Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor. Eur. J. Immunol. 1998; 28:582-8.
Alferink J, Lieberam I, Reindl W, et al. Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J. Exp. Med. 2003; 197:585-99.
Stutte S, Quast T, Gerbitzki N, et al. Requirement of CCL17 for CCR7 and CXCR4-dependent migration of cutaneous dendritic cells. Proc. Natl. Acad. Sci. USA 2010; 107:8736-41.

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$ 320.00
Cat# ASC11619
Availability: 5-7days
Bulk Size
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