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PRKCDBP Antibody

  • WB - PRKCDBP Antibody ASC11630
    Western blot analysis of PRKCDBP in A20 cell lysate with PRKCDBP antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • IHC - PRKCDBP Antibody ASC11630
    Immunohistochemistry of PRKCDBP in human spleen tissue with PRKCDBP antibody at 2.5 µg/ml.
  • IF - PRKCDBP Antibody ASC11630
    Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP antibody at 20 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q969G5
Other Accession NP_659477, 47132587
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 29 kDa
Application Notes PRKCDBP antibody can be used for detection of PRKCDBP by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 112464
Target/Specificity PRKCDBP; It is predicted to not cross-react with other members of the cavin family.
Reconstitution & Storage PRKCDBP antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsPRKCDBP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SRBC
Function Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2. Seems to have an immune potentiation function.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q91VJ2}.
Tissue Location Strongly expressed in mammary and epithelial cells.
Research Areas
Citations (0)

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PRKCDBP Antibody: The protein kinase C delta (PKC-δ) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.


Briand N, Dugail I, and Le Lay S. Cavin proteins: New players in the caveolae field. Biochimie 2011; 93:71-7.
Izumi Y, Hirai S, Tamai Y, et al. A protein kinase Cdelta-binding protein SRBC whose expression is induced by serum starvation. J. Biol. Chem. 1997; 272:7381-9.
McMahon K, Zajicek H, Li W, et al. SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function. EMBO J. 2009; 28:1001-15.
Bai L, Deng X, Li Q, et al. Down-regulation of the cavin family proteins in breast cancer. J. Cell Biochem. 2012; 113:322-8.

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$ 310.00
Cat# ASC11630
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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