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MTERFD3 Antibody

  • WB - MTERFD3 Antibody ASC11637
    Western blot analysis of MTERFD3 in human testis tissue lysate with MTERFD3 antibody at 1 µg/mL.
  • IHC - MTERFD3 Antibody ASC11637
    Immunohistochemistry of MTERFD3 in mouse testis tissue with MTERFD3 antibody at 2.5 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q49AM1
Other Accession NP_079474, 21314736
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 42 kDa

Observed: 40 kDa
Application Notes MTERFD3 Antibody can be used for detection of MTERFD3 by Western blot at 1 µg/mL.
Additional Information
Gene ID 80298
Target/Specificity MTERFD3; MTERFD3 antibody is predicted to not cross-react with other MTERFD protein family members.
Reconstitution & Storage MTERFD3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsMTERFD3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MTERFD3
Function Binds promoter DNA and regulates mitochondrial transcription. Required for normal levels of transcription, both for mRNA and tRNA. Required for normal mitochondrial protein synthesis, assembly of respiratory complexes and normal mitochondrial function (By similarity).
Cellular Location Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid
Tissue Location Expressed in skeletal muscle, heart, liver and pancreas.
Citations (0)

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MTERFD3 Antibody: Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD3 was initially identified through differential display analysis and is expressed primarily in heart, liver, pancreas and skeletal muscle. MTERFD3 is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription, and may be a serum-inhibitory factor.


Fernandez-Silva P, et al. The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions. EMBO J. 1997; 16:1066-79.
Chen Y, Zhou G, Yu M, et al. Cloning and functional analysis of human mTERFL encoding a novel mitochondrial transcription termination factor-like protein. Biochem. Biophys. Res. Commun. 2005; 337:1112-8.
Park CB, Asin-Cayuela J, Camara Y, et al. MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell 2007; 130:273-85.

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$ 310.00
Cat# ASC11637
(40 western blots)
Availability: 5-7days
Bulk Size
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