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PRRT2 Antibody

  • WB - PRRT2 Antibody ASC11641
    Western blot analysis of PRRT2 in mouse brain tissue lysate with PRRT2 antibody at 1 µg/mL.
  • IHC - PRRT2 Antibody ASC11641
    Immunohistochemistry of PRRT2 in rat brain tissue with PRRT2 antibody at 2.5 µg/ml.
  • IF - PRRT2 Antibody ASC11641
    Immunofluorescence of PRRT2 in rat brain tissue with PRRT2 antibody at 20 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z6L0
Other Accession NP_001243371, 374253783
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 43 kDa

Observed: 44 kDa
Application Notes PRRT2 Antibody can be used for detection of PRRT2 by Western blot at 1 µg/mL.
Additional Information
Gene ID 112476
Target/Specificity PRRT2; Multiple isoforms of PRRT2 are known to exist.
Reconstitution & Storage PRRT2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsPRRT2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRRT2
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse
Research Areas
Citations (0)

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PRRT2 Antibody: The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. While little is known of the function of this protein, mutations in PRRT2 have been shown to be the causative gene of paroxysmal kinesigenic dyskinesia, which is characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. Recent studies have shown that PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.


Wang JL, Cao L, Li XH, et al. Identification of PRRT2 as the causative gene of paroxysmal kinesigenic dyskinesias. Brain 2011; 134:3493-501.
Scheffer IE, Grinton BE, Heron SE, et al. PRRT2 phenotypic spectrum includes sporadic and fever-related infantile seizures. Neurology 2012; epub.

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$ 330.00
Cat# ASC11641
Availability: 5-7days
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