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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   COMMD7 Antibody   

COMMD7 Antibody

  • WB - COMMD7 Antibody ASC11721
    Western blot analysis of COMMD7 in mouse spleen tissue lysate with COMMD7 antibody at 1 µg/ml.
  • IHC - COMMD7 Antibody ASC11721
    Immunohistochemistry of COMMD7 in human spleen tissue with COMMD7 antibody at 5 µg/mL.
  • IF - COMMD7 Antibody ASC11721
    Immunofluorescence of COMMD7 in human spleen tissue with COMMD7 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86VX2
Other Accession NP_444269, 151101369
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 22 kDa

Observed: 21 kDa
Application Notes COMMD7 antibody can be used for detection of COMMD7 by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 149951
Target/Specificity COMMD7; COMMD7 antibody is human, mouse and rat reactive. Multiple transcript variants encoding different isoforms have been found for COMMD7.
Reconstitution & Storage COMMD7 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsCOMMD7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C20orf92
Function May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Associates with the NF-kappa-B complex and suppresses its transcriptional activity (PubMed:15799966).
Cellular Location Cytoplasmic vesicle
Tissue Location Widely expressed with highest expression in lung.
Research Areas
Citations (0)

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COMMD7 (COMM domain-containing protein 7) plays a role in the regulation NF-kappaB (1). It associates with the NF-kB complex and suppresses its transcriptional activity (2). COMMD7 contains 1 COMM domain and widely expressed with highest expression in lung (3). COMMD7 is a newly identified gene overexpressed in hepatocellular carcinoma (HCC) (4). COMMD7 is associated with tumor invasion and poor prognosis by NF-kappaB signaling pathway (4).


Maine GN and Burstein E. COMMD proteins and the control of the NF kappa B pathway. Cell Cycle 2007; 6:672-6.
Burstein E, Hoberg JE, Wilkinson AS, et al. COMMD proteins, a novel family of structural and functional homologs of MURR1. J. Biol. Chem. 2005; 280:22222-32.
Narindrasorasak S, Kulkarni P, Deschamps P, et al. Characterization and copper binding properties of human COMMD1 (MURR1). Biochemistry 2007; 46:3116-28.
Zheng L, Liang P, Li J, et al. ShRNA-targeted COMMD7 suppresses hepatocellular carcinoma growth. PLoS One 2012; 7:e45412.

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$ 330.00
Cat# ASC11721
Availability: 5-7days
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