|Other Accession||AFA36178, 375127553|
|Calculated MW||N/A KDa|
|Application Notes||Hantaan virus nucleocapsid antibody can detect 10ng Hantaan virus nucleocapsid peptide in ELISA at 1 µg/ml.|
|Reconstitution & Storage||Hantaan virus nucleocapsid antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.|
|Precautions||Hantaan Virus Nucleocapsid Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Virion. Note=Internal protein of virus particle|
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Provided below are standard protocols that you may find useful for product applications.
Hantaan virus (HNTV) is the prototype virus of the genus hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA virus that is the eiological agent of Korean hemorrhagic fever (1). Infection of cultured Vero E6 cells with HNTV induced expression of the heat shock protein HSP70. A substantial fraction of HSP70 was found to be associated with the HNTV nucleocapsid (NP) (2). Vero E6 cells that overexpress HSP70 show significantly reduced levels of NP and an increased resistance to infection by HNTV (2).
Arikawa J, Lapenotiere HF, Iacono-Connors L, et al. Coding properties of the S and M genome segments of Sapporo rat virus: comparison to other causative agents of hemorrhagic fever with renal syndrome. Virology 1990; 176:114-25.
Yu L, Ye L, Zhao R, et al. HSP70 induced by Hantavirus intfection interacts with viral nucleocapsid protein and its overexpression suppresses virus infection in Vero E6 cells. Am. J. Transl. Res. 2009; 1:367-80.
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