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ANGPTL3 Antibody

  • WB - ANGPTL3 Antibody ASC11817
    Western blot analysis of ANGPTL3 in human heart tissue lysate with ANGPTL3 antibody at (A) 1 and (B) 2 µg/ml.
  • IHC - ANGPTL3 Antibody ASC11817
    Immunohistochemistry of ANGPTL3 in rat heart tissue with ANGPTL3 antibody at 5 µg/mL.
  • IF - ANGPTL3 Antibody ASC11817
    Immunofluorescence of ANGPTL3 in rat heart tissue with ANGPTL3 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y5C1
Other Accession NP_055310, 7656888
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 51 kDa

Observed: 53 kDa
Application Notes ANGPTL3 antibody can be used for detection of ANGPTL3 by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry at 5 µg/mL. For Immunoflorescence start at 20 µg/mL.
Additional Information
Gene ID 27329
Target/Specificity ANGPTL3; ANGPTL3 antibody is human, mouse and rat reactive. ANGPTL3 antibody is predicted not to cross-react with other ANGPTL family proteins.
Reconstitution & Storage ANGPTL3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsANGPTL3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ANGPT5
Cellular Location Secreted.
Tissue Location Expressed principally in liver. Weakly expressed in kidney.
Research Areas
Citations (0)

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The angiopoietin-related protein 3 (ANGPTL3) is a member of a family of secreted proteins that function in angiogenesis (1). ANGPTL3 is processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis (2,3). Recent experiments have shown that a deficiency of ANGPTL3 is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids, suggesting that ANGPTL3 may also play a role in modulating glucose metabolism (4).


Conklin D, Gilbertson D, Taft DW, et al. Identification of a mammalian angiopoietin-related protein expressed specifically in liver. Genomics 1999; 62:477-82.
Koishi R, Ando Y, Ono M, et al. Angptl3 regulates lipid metabolism in mice. Nat. Genet. 2002; 30:151-7.
Camenisch G, Pisabarro MT, Sherman D, et al. ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo.J. Biol. Chem. 2002; 277:17281-90.
Robciuc MR, Maranghi M, Lahikainen A, et al. Angptl3 deficiency is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids. Arterioscler. Thromb. Vasc. Biol. 2013; 33:1706-13.

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$ 310.00
Cat# ASC11817
(40 western blots)
Availability: 5-7days
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