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NINJ1 Antibody

  • WB - NINJ1 Antibody ASC11852
    Western blot analysis of NINJ1 in human brain tissue lysate with NINJ1 antibody at 1 µg/ml.
  • IHC - NINJ1 Antibody ASC11852
    Immunohistochemistry of NINJ1 in mouse brain tissue with NINJ1 antibody at 5 µg/ml.
  • IF - NINJ1 Antibody ASC11852
    Immunofluorescence of NINJ1 in mouse brain tissue with NINJ1 antibody at 20 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92982
Other Accession NP_004139, 148922911
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 17 kDa

Observed: 16 kDa
Application Notes NINJ1 antibody can be used for detection of NINJ1 by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 4814
Target/Specificity NINJ1; NINJ1 antibody is human, mouse and rat reactive.
Reconstitution & Storage NINJ1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsNINJ1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NINJ1
Function Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin
Research Areas
Citations (0)

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Ninjurin-1 (NINJ1) is a homophilic adhesion molecule that is strongly induced in dorsal root ganglion (DRG) and Schwann cells following nerve injury and promotes neurite outgrowth of DRG neurons (1,2), suggesting that NINJ1 may play a role in nerve regeneration. NINJ1 is transcriptionally regulated by p53 and is induced by DNA damage in a p53-dependent manner. A deficiency of NINJ1 increases p53 expression, suppresses cell proliferation, but enhances apoptosis and premature senescence in a p53-dependent manner as well as radiation-induced cell mortality (3).


Araki T and Milbrandt J. Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth. Neuron 1996; 17:353-61.
Araki T, Zimonjic DB, Popescu NC, et al. Mechanism of homophilic binding mediated by ninjurin, a novel widely expressed adhesion molecule. J. Biol. Chem. 1997; 212:21373-80.
Cho SJ, Rossi A, Jung YS, et al. Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, sensecence, and radiation-induced mortality. Proc. Natl. Acad. Sci. USA 2013; 110:9362-7.

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$ 310.00
Cat# ASC11852
(40 western blots)
Availability: 5-7days
Bulk Size
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