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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KCNK1 Antibody   

KCNK1 Antibody

  • WB - KCNK1 Antibody ASC11868
    Western blot analysis of KCNK1 in 3T3 cell lysate with KCNK1 antibody at 1 µg/ml.
  • IHC - KCNK1 Antibody ASC11868
    Immunohistochemistry of KCNK1 in mouse brain tissue with KCNK1 antibody at 5 µg/ml.
  • IF - KCNK1 Antibody ASC11868
    Immunofluorescence of KCNK1 in mouse brain tissue with KCNK1 antibody at 20 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00180
Other Accession NP_002236, 4504847
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 37 kDa

Observed: 35 kDa
Application Notes KCNK1 antibody can be used for detection of KCNK1 by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 3775
Target/Specificity KCNK1; KCNK1 antibody is human, mouse and rat reactive. KCNK1 antibody is predicted to not cross-react with other KCNK proteins.
Reconstitution & Storage KCNK1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsKCNK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNK1
Synonyms HOHO1, KCNO1, TWIK1
Function Weakly inward rectifying potassium channel that contributes to the regulation of the resting membrane potential.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney (PubMed:8605869).
Research Areas
Citations (0)

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The potassium channel, subfamily K, member 1 (KCNK1), is member of the superfamily of potassium channel proteins containing two pore-forming P domains (1,2). KCNK1 is a ubiquitous human weakly inward rectifying K+ channel that is widely expressed in human tissues, and particularly abundant in brain and heart (1). Both KCNK1 and the related protein KCNK2 contribute significantly to the passive conductance of hippocampal astrocytes (3).


Lesage F, Guillemare E, Fink M, et al. TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure. EMBO J. 1996; 15:1004-11.
Goldstein SA, Bockenhauer D, O’Kelly I, et al. Potassium leak channels and the KCNK family of two-P domain subunits. Nat. Rev. Neurosci. 2001; 2:175-84.
Zhou M, Xu G, Xie M, et al. TWIK-1 and TREK-2 are potassium channels contributing significantly to astrocyte passive conductance in rat hippocampal slides. J. Neurosci. 2009; 29:8551-64.

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$ 310.00
Cat# ASC11868
Availability: 5-7days
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