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RNF121 Antibody

  • WB - RNF121 Antibody ASC11948
    Western blot analysis of RNF121 in MCF7 cell lysate with RNF121 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
  • ICC - RNF121 Antibody ASC11948
    Immunocytochemistry of RNF121 in MCF7 cells with RNF121 antibody at 10 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H920
Other Accession NP_060790, 21361732
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 24, 27, 36 kDa

Observed: 28 kDa
Application Notes RNF121 antibody can be used for detection of RNF121 by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunocytochemistry at 10 µg/ml.
Additional Information
Gene ID 552978
Target/Specificity RNF121; RNF121 antibody is human, mouse and rat reactive. Multiple isoforms of RNF121 are known to exist.
Reconstitution & Storage RNF121 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsRNF121 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNF121
Cellular Location Membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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RNF121 is an evolutionarily conserved E3 ligase ring finger protein that is expressed in the endoplasmic reticulum (1). It acts downstream of the unfolded protein response regulator protein kinase-like endoplasmic reticulum kinase (PERK). Overexpression of RNF121 during the early stages of gonad development led to aberrations in germline development and gonad migration, suggesting that it plays a role in endoplasmic reticulum-associated degradation machinery (1).


Darom A, Bening-Abu-Shach U, and Broday L. RNF-121 is an endoplasmic reticulum-membrane E3 ubiquitin ligase involved in the regulation of B-integrin. Mol. Biol. Cell 2010; 21:1788-98.

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$ 310.00
Cat# ASC11948
(40 western blots)
Availability: 5-7days
Bulk Size
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