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ABL2 Antibody (monoclonal) (M09)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT1014a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ABL2 Antibody (monoclonal) (M09) - Product info | |
| Application | IF, WB
|
| Primary Accession | P42684 |
| Reactivity | Human |
| Isotype | IgG3 Kappa |
| Clone Names | 5C6 |
| Calculated MW | 128343 Da |
ABL2 Antibody (monoclonal) (M09) - Additional info | |
| Gene ID 27 | |
| Other Names ABLL, ARGv-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) | |
| Target/Specificity ABL2 (AAH65912, 743 a.a. ~ 842 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABL2 Antibody (monoclonal) (M09) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABL2 Antibody (monoclonal) (M09) - Related products
AP3018a: Phospho-ABL-Y412 Antibody
ABL2 Antibody (monoclonal) (M09) - Application data
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Immunofluorescence of monoclonal antibody to ABL2 (AT1014a) on HeLa cell . [antibody concentration 10 ug/ml]
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ABL2 monoclonal antibody (M09), clone 5C6 Western Blot analysis of ABL2 expression in K-562 ( Cat # L009V1 ).
ABL2 Antibody (monoclonal) (M09) - Research Areas
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BACKGROUND
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
REFERENCES
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Successful treatment using omacetaxine for a patient with CML and BCR-ABL1 [corrected] 35INS. Mahadeo KM, et al. Blood, 2010 May 6. PMID 20448119.NMR structure of F-actin-binding domain of Arg/Abl2 from Homo sapiens. Liu G, et al. Proteins, 2010 Apr. PMID 20077570.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Reciprocal regulation of Abl and receptor tyrosine kinases. Srinivasan D, et al. Cell Signal, 2009 Jul. PMID 19275932.
