ADAMTS8 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant ADAMTS8.
|Application ||WB, E|
|Calculated MW||96460 Da|
|Other Names||A disintegrin and metalloproteinase with thrombospondin motifs 8, ADAM-TS 8, ADAM-TS8, ADAMTS-8, 3424-, METH-2, METH-8, ADAMTS8, METH2|
|Target/Specificity||ADAMTS8 (NP_008968, 781 a.a. ~ 890 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||ADAMTS8 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.
1.EXTRACELLULAR AND MEMBRANE-ASSOCIATED PROSTATE CANCER MARKERSKlee, George G. ;Vasmatzis, George;Kosari, Farhad;Klee, Eric W.FreshPatents.com
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