APEG1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant APEG1.
|Application ||WB, E|
|Calculated MW||354289 Da|
|Other Names||Striated muscle preferentially expressed protein kinase, Aortic preferentially expressed protein 1, APEG-1, SPEG, APEG1, KIAA1297|
|Target/Specificity||APEG1 (AAH06346, 1 a.a. ~ 113 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||APEG1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes a protein with similarity to members of the myosin light chain kinase family. This protein family is required for myocyte cytoskeletal development. Studies in mouse have determined that a lack of this protein affected myocardial development. Multiple alternatively spliced transcript variants have been reported for this gene, but the full-length nature of only two variants that encode different protein isoforms has been defined.
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.The human desmin locus: gene organization and LCR-mediated transcriptional control. Tam JL, et al. Genomics, 2006 Jun. PMID 16545539.X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1). Manjasetty BA, et al. BMC Struct Biol, 2005 Dec 14. PMID 16354304.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.
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