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ARHGEF11 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant ARHGEF11.

  • WB - ARHGEF11 Antibody (monoclonal) (M02) AT1186a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - ARHGEF11 Antibody (monoclonal) (M02) AT1186a
    ARHGEF11 monoclonal antibody (M02), clone 2F4. Western Blot analysis of ARHGEF11 expression in human colon.
  • E - ARHGEF11 Antibody (monoclonal) (M02) AT1186a
    Detection limit for recombinant GST tagged ARHGEF11 is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15085
Other Accession BC057394
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2F4
Calculated MW 167704 Da
Additional Information
Gene ID 9826
Other Names Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF, ARHGEF11, KIAA0380
Target/Specificity ARHGEF11 (AAH57394, 651 a.a. ~ 750 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsARHGEF11 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.


Genome-wide association study to identify genetic variants present in Japanese patients harboring intracranial aneurysms. Akiyama K, et al. J Hum Genet, 2010 Jul 8. PMID 20613766.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.PYK2/PDZ-RhoGEF links Ca2+ signaling to RhoA. Ying Z, et al. Arterioscler Thromb Vasc Biol, 2009 Oct. PMID 19759375.The amino acid motif L/IIxxFE defines a novel actin-binding sequence in PDZ-RhoGEF. Banerjee J, et al. Biochemistry, 2009 Aug 25. PMID 19618964.On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF. Zheng M, et al. BMC Struct Biol, 2009 May 21. PMID 19460155.

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$ 315.00
Cat# AT1186a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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