ASAH1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant ASAH1.
|Application ||WB, IHC, E|
|Calculated MW||44660 Da|
|Other Names||Acid ceramidase, AC, ACDase, Acid CDase, Acylsphingosine deacylase, N-acylsphingosine amidohydrolase, Putative 32 kDa heart protein, PHP32, Acid ceramidase subunit alpha, Acid ceramidase subunit beta, ASAH1, ASAH|
|Target/Specificity||ASAH1 (NP_808592, 25 a.a. ~ 124 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||ASAH1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.
1.Ceramide biosynthesis and metabolism in trophoblast syncytialization.Singh AT, Dharmarajan A, Aye IL, Keelan JA.Mol Cell Endocrinol. 2012 May 28.
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