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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ASL Antibody (monoclonal) (M01)   

ASL Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant ASL.

  • WB - ASL Antibody (monoclonal) (M01) AT1214a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (76.78 KDa) .
  • WB - ASL Antibody (monoclonal) (M01) AT1214a
    Western Blot analysis of ASL expression in transfected 293T cell line by ASL monoclonal antibody (M01), clone 4C5-1F2.

    Lane 1: ASL transfected lysate(51.7 KDa).
    Lane 2: Non-transfected lysate.
  • IF - ASL Antibody (monoclonal) (M01) AT1214a
    Immunofluorescence of monoclonal antibody to ASL on HeLa cell. [antibody concentration 5 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04424
Other Accession BC008195
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 4C5-1F2
Calculated MW 51658 Da
Additional Information
Gene ID 435
Other Names Argininosuccinate lyase, ASAL, Arginosuccinase, ASL
Target/Specificity ASL (AAH08195, 1 a.a. ~ 464 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsASL Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.


1.Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma.Syed N, Langer J, Janczar K, Singh P, Lo Nigro C, Lattanzio L, Coley HM, Hatzimichael E, Bomalaski J, Szlosarek P, Awad MCell Death Dis. 2013 Jan 17;4:e458. doi: 10.1038/cddis.2012.197.

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$ 315.00
Cat# AT1214a
(40 western blots)
Availability: 7-10 days
Bulk Size
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