BACH1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant BACH1.
|Application ||WB, E|
|Calculated MW||81958 Da|
|Other Names||Transcription regulator protein BACH1, BTB and CNC homolog 1, HA2303, BACH1|
|Target/Specificity||BACH1 (NP_996749, 396 a.a. ~ 492 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||BACH1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.
Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1. Miyazaki T, et al. Cancer Sci, 2010 Jun. PMID 20345481.BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control. Gong Z, et al. Mol Cell, 2010 Feb 12. PMID 20159562.MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins. Hou W, et al. Hepatology, 2010 May. PMID 20127796.A role for Bach1 and HO-2 in suppression of basal and UVA-induced HO-1 expression in human keratinocytes. Zhong JL, et al. Free Radic Biol Med, 2010 Jan 15. PMID 19874887.Prolonged cigarette smoke exposure decreases heme oxygenase-1 and alters Nrf2 and Bach1 expression in human macrophages: roles of the MAP kinases ERK(1/2) and JNK. Goven D, et al. FEBS Lett, 2009 Nov 3. PMID 19822148.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.