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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   BAIAP2L1 Antibody (monoclonal) (M01)   

BAIAP2L1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant BAIAP2L1.

  • WB - BAIAP2L1 Antibody (monoclonal) (M01) AT1264a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (38.28 KDa) .
  • WB - BAIAP2L1 Antibody (monoclonal) (M01) AT1264a
    BAIAP2L1 monoclonal antibody (M01), clone 2A4. Western Blot analysis of BAIAP2L1 expression in HeLa.
  • WB - BAIAP2L1 Antibody (monoclonal) (M01) AT1264a
    BAIAP2L1 monoclonal antibody (M01), clone 2A4. Western Blot analysis of BAIAP2L1 expression in Hela S3 NE.
  • IHC - BAIAP2L1 Antibody (monoclonal) (M01) AT1264a
    Immunoperoxidase of monoclonal antibody to BAIAP2L1 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml]
  • E - BAIAP2L1 Antibody (monoclonal) (M01) AT1264a
    Detection limit for recombinant GST tagged BAIAP2L1 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UHR4
Other Accession NM_018842
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2A4
Calculated MW 56883 Da
Additional Information
Gene ID 55971
Other Names Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, BAI1-associated protein 2-like protein 1, Insulin receptor tyrosine kinase substrate, BAIAP2L1, IRTKS
Target/Specificity BAIAP2L1 (NP_061330, 398 a.a. ~ 511 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsBAIAP2L1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.


Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. Voss M, et al. BMC Immunol, 2009 Oct 6. PMID 19807924.Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation. Vingadassalom D, et al. Proc Natl Acad Sci U S A, 2009 Apr 21. PMID 19366662.IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions. Scita G, et al. Trends Cell Biol, 2008 Feb. PMID 18215522.Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity. Galligan CL, et al. Genes Immun, 2007 Sep. PMID 17568789.Characterisation of IRTKS, a novel IRSp53/MIM family actin regulator with distinct filament bundling properties. Millard TH, et al. J Cell Sci, 2007 May 1. PMID 17430976.

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$ 315.00
Cat# AT1264a
(40 western blots)
Availability: 7-10 days
Bulk Size
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