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BTG4 Antibody (monoclonal) (M07)

Mouse monoclonal antibody raised against a full length recombinant BTG4.

     
  • IF - BTG4 Antibody (monoclonal) (M07) AT1318a
    Immunofluorescence of monoclonal antibody to BTG4 on HeLa cell . [antibody concentration 10 ug/ml]
    detail
  • WB - BTG4 Antibody (monoclonal) (M07) AT1318a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (48.4 KDa) .
    detail
  • WB - BTG4 Antibody (monoclonal) (M07) AT1318a
    Western Blot analysis of BTG4 expression in transfected 293T cell line by BTG4 monoclonal antibody (M07), clone 1A6.

    Lane 1: BTG4 transfected lysate(24 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF
Primary Accession Q9NY30
Other Accession BC031045
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 1A6
Calculated MW 25970 Da
Additional Information
Gene ID 54766
Other Names Protein BTG4, BTG family member 4, Protein PC3b, BTG4, PC3B
Target/Specificity BTG4 (AAH31045, 1 a.a. ~ 206 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsBTG4 Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein can induce G1 arrest in the cell cycle.

References

A potentially functional polymorphism in the promoter region of miR-34b/c is associated with an increased risk for primary hepatocellular carcinoma. Xu Y, et al. Int J Cancer, 2010 Mar 22. PMID 20309940.Frequent promoter hypermethylation and transcriptional downregulation of BTG4 gene in gastric cancer. Dong W, et al. Biochem Biophys Res Commun, 2009 Sep 11. PMID 19576178.Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Toyota M, et al. Cancer Res, 2008 Jun 1. PMID 18519671.Identification of a potential role for POU2AF1 and BTG4 in the deletion of 11q23 in chronic lymphocytic leukemia. Auer RL, et al. Genes Chromosomes Cancer, 2005 May. PMID 15672409.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.

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$ 350.00
Cat# AT1318a
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Availability: 7-10 days
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