C1GALT1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant C1GALT1.
|Application ||WB, IHC, E|
|Calculated MW||42203 Da|
|Other Names||Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, B3Gal-T8, Core 1 O-glycan T-synthase, Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1, 3-galactosyltransferase 1, Beta-1, 3-galactosyltransferase, Core 1 beta1, 3-galactosyltransferase 1, C1GalT1, Core 1 beta3-Gal-T1, C1GALT1|
|Target/Specificity||C1GALT1 (NP_064541, 264 a.a. ~ 363 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||C1GALT1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.
1.Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrier.Argueso P, Guzman-Aranguez A, Mantelli F, Cao Z, Ricciuto J, Panjwani N.J Biol Chem. 2009 Aug 21;284(34):23037-45. Epub 2009 Jun 25.
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