CD38 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant CD38.
|Application ||WB, IF, E|
|Calculated MW||34328 Da|
|Other Names||ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, ADPRC 1, Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10, CD38, CD38|
|Target/Specificity||CD38 (AAH07964, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||CD38 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion,signal transduction and calcium signaling.
Mouse embryonic fibroblasts from CD38 knockout mice are resistant to oxidative stresses through inhibition of reactive oxygen species production and Ca(2+) overload. Ge Y, et al. Biochem Biophys Res Commun, 2010 Aug 20. PMID 20638362.Two genetic variants of CD38 in subjects with autism spectrum disorder and controls. Munesue T, et al. Neurosci Res, 2010 Jun. PMID 20435366.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.CD38/CD31 interactions activate genetic pathways leading to proliferation and migration in chronic lymphocytic leukemia cells. Deaglio S, et al. Mol Med, 2010 Mar. PMID 19956559.Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Satake W, et al. Nat Genet, 2009 Dec. PMID 19915576.
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