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CDC37L1 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a full-length recombinant CDC37L1.
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Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (62.81 KDa) .
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CDC37L1 monoclonal antibody (M03), clone 1D4. Western Blot analysis of CDC37L1 expression in HepG2 ( (Cat # AT1462a )
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Detection limit for recombinant GST tagged CDC37L1 is 0.03 ng/ml as a capture antibody.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q7L3B6 |
| Other Accession | BC014133 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 1D4 |
| Calculated MW | 38835 Da |
| Gene ID | 55664 |
|---|---|
| Other Names | Hsp90 co-chaperone Cdc37-like 1, Hsp90-associating relative of Cdc37, CDC37L1, CDC37B, HARC |
| Target/Specificity | CDC37L1 (AAH14133, 1 a.a. ~ 337 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | CDC37L1 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CDC37L1 is a cytoplasmic phosphoprotein that exists in complex with HSP90 (HSPCA; MIM 140571) as well as several other proteins involved in HSP90-mediated protein folding (Scholz et al., 2001 [PubMed 11413142]).
References
Importance of the C-terminal domain of Harc for binding to Hsp70 and Hop as well as its response to heat shock. Cartledge K, et al. Biochemistry, 2007 Dec 25. PMID 18052042.Domain-mediated dimerization of the Hsp90 cochaperones Harc and Cdc37. Roiniotis J, et al. Biochemistry, 2005 May 3. PMID 15850399.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.Identification and characterization of Harc, a novel Hsp90-associating relative of Cdc37. Scholz GM, et al. J Biol Chem, 2001 Aug 17. PMID 11413142.Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. Suzuki Y, et al. Gene, 1997 Oct 24. PMID 9373149.
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