CNOT3 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant CNOT3.
|Application ||WB, IF, E|
|Calculated MW||81872 Da|
|Other Names||CCR4-NOT transcription complex subunit 3, CCR4-associated factor 3, Leukocyte receptor cluster member 2, CNOT3, KIAA0691, LENG2, NOT3|
|Target/Specificity||CNOT3 (NP_055331, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||CNOT3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1.Identification of Ccr4-Not complex components as regulators of transition from partial to genuine induced pluripotent stem cells.Kamon M, Katano M, Hiraki-Kamon K, Hishida T, Nakachi Y, Mizuno Y, Okazaki Y, Suzuki A, Hirasaki M, Ueda A, Nishimoto M, Kato H, Okuda AStem Cells Dev. 2013 Nov 8.2.The Anti-Proliferative Activity of BTG/TOB Proteins Is Mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) Deadenylase Subunits of the Ccr4-Not Complex.Doidge R, Mittal S, Aslam A, Winkler GS.PLoS One. 2012;7(12):e51331. doi: 10.1371/journal.pone.0051331. Epub 2012 Dec 7.3.The Ccr4-not deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation.Aslam A, Mittal S, Koch F, Andrau JC, Winkler GS.Mol Biol Cell. 2009 Sep;20(17):3840-50. Epub 2009 Jul 15.
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