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COPS3 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant COPS3.

  • WB - COPS3 Antibody (monoclonal) (M02) AT1592a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - COPS3 Antibody (monoclonal) (M02) AT1592a
    COPS3 monoclonal antibody (M02), clone 2D10 Western Blot analysis of COPS3 expression in HeLa ( (Cat # AT1592a )
  • WB - COPS3 Antibody (monoclonal) (M02) AT1592a
    COPS3 monoclonal antibody (M02), clone 2D10. Western Blot analysis of COPS3 expression in PC-12 ( (Cat # AT1592a )
  • WB - COPS3 Antibody (monoclonal) (M02) AT1592a
    Western Blot analysis of COPS3 expression in transfected 293T cell line by COPS3 monoclonal antibody (M02), clone 2D10.

    Lane 1: COPS3 transfected lysate(47.9 KDa).
    Lane 2: Non-transfected lysate.
  • IF - COPS3 Antibody (monoclonal) (M02) AT1592a
    Immunofluorescence of monoclonal antibody to COPS3 on HeLa cell. [antibody concentration 20 ug/ml]
  • E - COPS3 Antibody (monoclonal) (M02) AT1592a
    Detection limit for recombinant GST tagged COPS3 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UNS2
Other Accession NM_003653
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2D10
Calculated MW 47873 Da
Additional Information
Gene ID 8533
Other Names COP9 signalosome complex subunit 3, SGN3, Signalosome subunit 3, JAB1-containing signalosome subunit 3, COPS3, CSN3
Target/Specificity COPS3 (NP_003644, 324 a.a. ~ 422 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCOPS3 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17.


Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.The ubiquitin- and proteasome-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs. Neuss H, et al. J Mol Med, 2007 Sep. PMID 17429597.Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Angers S, et al. Nature, 2006 Oct 5. PMID 16964240.A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. Jin J, et al. Mol Cell, 2006 Sep 1. PMID 16949367.

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$ 315.00
Cat# AT1592a
(40 western blots)
Availability: 7-10 days
Bulk Size
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